The speaker will briefly review the natural history of HIV and the different target sites for drug therapy before discussing the current DHHS guidelines. A brief review of the pharmacology of the different antiretrovirals will be presented including the pros and cons of each agent. Consideration of the patient's baseline co morbidities will also be discussed.
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The first decade of the HIV epidemic revealed the power of opportunistic infections (OIs) in a body whose immune system was decimated by HIV. It was only in the later half of that first decade when we began to understand the concept of chemoprophylaxis against OIs. With the introduction of highly active antiretroviral therapy (HAART) in the second decade of the epidemic, the incidence of OIs dropped and the life expectancy of those infected increased substantially. Chemoprophylaxis against OIs is still paramount in certain HIV populations at risk, but need not be lifelong in many, as HAART can restore immune function. Current guidelines in the primary and secondary prophylaxis of the major OIs will be presented, including when to discontinue this mode of prevention.
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Adult Vaccines
Mobeen Rathore, MD

HIV infected individuals are at an increased risk for opportunistic infections. Many of these infections are preventable with currently available vaccines. This lecture will discuss the available vaccines, their indications, contraindications and cautions for use. Important concepts in immunizations as it relates to the immune compromised, will also be discussed.
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Slides provided in .pdf format, by request of the speaker.

Interventions for the reduction of perinatal transmission of HIV have significantly reduced mother-to-child transmission of the virus. This lecture will review current recommendations for the management HIV-infected pregnant women including preferred antiretroviral regimens, indications for cesarean section, and complications of antiretroviral therapy in pregnancy.
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Hepatitis Co-infection
Sandra G. Gompf, MD, FACP

As the long-term survival in HIV infection has improved, chronic illnesses such as hepatitis have emerged as significant agents of cormorbidity and early mortality. The speaker will present an overview of the epidemiology of viral hepatitis in HIV and recommendations for screening and prevention. Treatment of hepatitis B and C continues to evolve, especially in HIV. An overview of current management will be discussed.
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Tips for Assessing Drug Interactions (Track:- Medication/Pharmacy- Related Topics)
Todd S. Wills, MD

Recognition of drug interactions is especially important in the care of HIV infected patients. Many patients are on a number of medications for chronic conditions such as hyperlipidemia, depression, seizure disorders, or chronic pain. Additionally, many patients require polypharmacy for the treatment of HIV, concurrent opportunistic infections or disease-related complications. This lecture will discuss the most frequently encountered drug interactions for HIV care providers and discuss tools for the recognition and management of these.
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Resistance Testing (Track:- Medication/Pharmacy- Related Topics)
Joanne J. Orrick, PharmD, BCPS

This presentation will provide a basic overview of resistance testing for the practitioner who is just starting out in the treatment of HIV-infected patients or those wanting a refresher on the fundamentals of resistance testing. The following topics will be reviewed in this presentation: guidelines for the use of resistance testing, overview of available resistance tests, review of most common resistance mutations, and resources for resistance testing interpretation.
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Mental Health Issues/Substance Abuse
Carlos Santana, MD

Mental health issues and substance abuse have a significant impact on the care of HIV-infected patients. Many patients acquire their infection through high-risk activities which are the consequence of psychiatric co-morbidities. The medical management of these patients is further complicated by poor adherence to antiretroviral regimens, complex therapeutic regimens, and often, a lack of access to mental health services. This lecture will review the challenges and progress made in the care of such complicated patients.
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STD Treatment Update
Jeffrey Beal, M.D

This session will provide an overview of treatment of STDs most commonly encountered in HIV-infected patients. Important changes in the 2006 CDC STD Guidelines will be presented.
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